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Multi-ancestry phenome-wide association of complement component 4 variation with psychiatric and brain phenotypes in youth.
Leanna M Hernandez, Minsoo Kim, Pan Zhang, Richard A I Bethlehem, Gil Hoftman, Robert Loughnan, Diana Smith, Susan Y Bookheimer, Chun Chieh Fan, Carrie E Bearden, Wesley K Thompson, Michael J Gandal
Apr 07, 2023
Background
Increased expression of the complement component 4A (C4A) gene is associated with a greater lifetime risk of schizophrenia. In the brain, C4A is involved in synaptic pruning; yet, it remains unclear the extent...
Brain complement Genetics Schizophrenia Gene Expression Psychosis Neuroimaging Humans Cognition Mental Disorders Phenotype Complement C4
Published by: Genome biology
Can E-Government Serve as a Tool for Public Authorities to Manage Public Resources More Efficiently?
Innovations in the field of telecommunications and technological development in information processing affect the provision of public services. One of the main priorities of governments is to achieve greater efficiency in the...
Published by: IGI Global
Data-Centric UML Profile for Wireless Sensors
Modelling WSN data behaviour is relevant since it would allow to evaluate the capacity of an application for supplying the user needs, moreover, it could enable a transparent integration with different data-centric information...
Environmental Technologies Environmental, Agricultural, and Physical Sciences Environmental Science and Technologies
Published by: IGI Global